Are Generic Drugs as Good as Brand Name?

Faced with rising health care costs and a recession, many people are looking for ways to cut back on their monthly medical bills. One way we can do this is by choosing generic over brand name drugs. But some have reservations about opting for the cheaper choice, assuming that more money means a better pill. Are they the same?

What Is a Generic?
A generic drug contains the exact same active ingredient as a brand name drug. The reason it’s cheaper is because the pharmaceutical patent on the name brand drug has expired and other companies are therefore able to manufacture it. A patent for a new drug lasts around twenty years; it protects the research, development, marketing, and promotion and means the company has the sole right to sell the drug. Once the patent is about to expire, however, other companies can apply to make and sell the generic version. They haven’t had to pay for the research or marketing, so their costs—and yours—are substantially lower.

Competition among generic makers can also keep the price low. Currently, about half of all prescriptions in the United States are filled with generic drugs.

Cheap Pills, Same Thrills
Because generics contain the same active ingredients as the brand name, they are bioequivalent, meaning they have the same pharmacological activity and the same risks and benefits of the brand name drug. The Food and Drug Administration requires that generics are the same in dosage, safety, purity, strength, route of administration, quality, and performance. In fact, many drug companies that make the brand name drug also have a hand in manufacturing the generic.

A recent review in the Journal of the American Medical Association proved the clinical equivalence of generic and brand name drugs by looking at those used in cardiovascular disease. Analyzing forty-seven studies, they concluded that there was no superiority of brand name drugs over generics.

Looks Aren’t Everything
Despite this, a substantial number of people and doctors question the interchangeability of generics for brand name. Part of this can be traced to appearances. Although generics contain the same active drug, they often look different in terms of shape, color, or taste. This is because the maker of the drug has trademarked the appearance and name of a product and generic makers can’t duplicate this, even though the active ingredient is copied. (Patents expire, trademarks don’t.)

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07.18.2009
Shalaseia
I take medicine everyday for certaine things and I take vitamins as well. One of the most importatnt things I HAVE to take are IRON supplements because for some reason I am severly Anemic and without them I will die. I can tell the difference when I take the name brand or the pharmacy brand. There was also another brand I tried, all with same stregnth but each with different material added to help it bind together. I cannot stray from the name brand at all or I will feel the effects immediately. So please talke to you doctors and read, read, read the labels because the strenght maybe the but there will be other additives that can interact with your otehr medicine. Also let your doctor know when you are taking supplements becasue they can have a bad interactions with your prescribed medicine....Take care...
12.24.2008
Kimberly
There are differences in the generic drugs in comparison to the brand names. As stated previously, the difference needs to be discussed with your pharmacist if your healthcare provider is not aware. Some cardiac drugs fall into the category where many patients need the brand, not the generic. A slight change in the formula can make a big difference in the patient's condition. That is why physicians and nurse practitioners (like myself) will write a script that states "DAW" which is "dispense as wriiten." This let's the pharmacist know not to substitute with a generic. Furthermore, if you are taking a drug that falls in this category, your healthcare provider can contact your insurance carrier to argue the point of the brand name drug vs the generic. It still may cost you more in a co-pay, but at least the insurance carrier will allow you to have the medication as prescribed.
12.24.2008
KristinaCO
I take Synthroid for hypothyroidism and my doctor always presribes the brand name, not the generic Levothyroxine. In fact, the Pharmacist said that something in the two drugs is different and if you start out on one your body adjusts to it, so you must remain on the one you started on. The dosage for the drug is in micrograms, not miligrams, and targets your endocrine system with incredibly minor adjustments that have a big impact on your physiology. IIn fact, once I was given the generic by accident and didn't notice becuase the pills look so similar. I had tremendous problems with shakiness and sleep so I went to the Dr. to be retested and found out the cause was actually the generic instead of the brand name mistake. t is interesting to me that this is a very real case of the brand and generic NOT being interchangable.
12.23.2008
Roy Johnson
I beg to differ with the comments regarding relative quality. SOME generic drugs have equal quality, despite different appearance, but FDA regulations allow generics to be made with varying ingredients which may be up to 50% different in amount from the original. With some drugs the differences are insignificant, but with others the exact formulation can be critical. Consult your pharmacist and doctor, because some generics are not advisable. I know because some of my medications are like that.
12.15.2008
Pam
Brie, this is a superb article and brings important information to the pharmaceutical consumer. May I add one caveat? This has to do with drugs in liquid form, and comes from first-hand knowledge and experience from my career days. Most liquid drugs contain some form of flavoring in order to make the liquid palatable, especially for children. In my professional capacity at a flavor/fragrance house, I received a call from a pediatrician trying to track down why switching from a brand-name liquid drug to the generic version caused his patient to have an allergic reaction. The only difference between the two was that the flavoring in the brand name drug was provided by my firm, and that in the generic was provided by another firm. The formula for their flavoring was different from ours, not an unusual occurrence. He had the formula info from the other supplier, and I gave him ours, so he was able to isolate the differences, and help his patient. Not common, but it does happen.
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