I’ve had friends and family with diseases like cancer, lupus, bipolar, and diabetes, but I’ve never known anyone with a disease I could laugh at. They say laughter is the best medicine; that’s good news for the sufferers of these diseases—at least they’ve got that going for them.
1) Maple Syrup Urine Disease (MSUD)
To answer your question, yes, your pee does smell like maple syrup. Other symptoms include lethargy, coma, avoiding food, and mental retardation. If left untreated, this disease can kill you and would make for an embarrassing obituary … Jeremy White, loving father, son, husband, lost his brave battle against Maple Syrup Urine Disease.
This disease is a metabolism disorder that makes the body incapable of breaking down particular proteins. Studies conducted since 1979 (Georgia) show that MSUD affects approximately 1 in every 120,000 live births and occurs in all ethnic groups worldwide. It’s genetic, so if your baby has pee that smells like it could be poured over waffles, get that baby to the hospital—stat!
2) Exploding Head Syndrome
I’m sure many of you get the same mental image I do when reading the name of this disease. It’s actually not that funny of a disease, but I couldn’t resist that name. Well, it’s kinda funny … the sufferer of Exploding Head Syndrome experiences a sudden loud noise in his head, either right before falling asleep or in the middle of sleep. It’s like an explosion (or cymbal crash) in your brain, but there’s no pain involved and no one else hears it (that’s got to be a lonely feeling).
A report by a British physician in 1988 might be the first description of exploding head syndrome. The good news is that doctors emphasize its benign nature—yeah, it’s traumatizing and can feel like a stroke, but it won’t really hurt you. Don’t get too stressed out—anxiety might trigger it, as can extreme fatigue. Also, women get it more than men, especially when they’re being bitchy. (Okay, I made that last part up.)
3) Jumping Frenchmen of Maine Disorder
This oddly named disease occurs due to a genetic mutation that prevents “exciting” signals in the nervous system from being regulated. It was first discovered in 1878 in a French-Canadian lumberjack population in the Moosehead Lake area of Maine.



























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